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Safety and side effects always guide these decisions
Persistent severe reflux over months can lead to esophageal inflammation (esophagitis) or Barrett's esophagus in susceptible individuals
10.1186/S12935-022-02496-Z 70 WangZ.LuoJ.ZhangY.XunP.ChenZ
On one hand, individuals with BD may have a higher likelihood of developing metabolic disturbancesdue to a combination of lifestyle-related factors, such as physical inactivity, emotional eating, smoking, and disrupted sleep patterns, exacerbated during mood episodes ( On the other hand, the presence of MetS may negatively influence the clinical course of BD
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