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When oxidative stress occurs, it damages neurons, disrupts signaling, and contributes to the progression of neurodegenerative disorders such as: Alzheimers disease Parkinsons disease Multiple sclerosis (MS) Amyotrophic lateral sclerosis (ALS) Over time, excessive oxidative damage impairs mitochondrial function the energy center of brain cells and accelerates neuronal decline

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Mice with no gene for beta-3 adrenergic receptors didnt experience changes in body composition or an increase in lipolysis [2]