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Within this framework, our observation of reduced thalamic GSH during the interictal phase may be regarded as a candidate neurochemical correlate of these chronic, between-attack thalamic changes, possibly reflecting cumulative oxidative burden in a region chronically exposed to trigeminovascular input over years of recurrent attacks
Why the long off phase: the 4 month pause is built into the protocol
Hossain M, Mazzone P, Tierney W, Cucullo L
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