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In the field of glucose and energy metabolism, metabolomic studies have identified glucose as a differential metabolite with potential biomarker value (141)
Tumor-selective receptor engagement provides another solution, as illustrated by CAIX-targeted Supra-LYTACs that preferentially function in hypoxic tumor regions [72]
The pathophysiology of neuropathic pain varies and includes ectopic activity in damaged nerves or in adjacent nerves, dorsal root ganglion (DRG) or central pathways, and peripheral and central sensitisation involving numerous molecular mechanisms
Bossart M, Wagner M, Elvert R, Evers A, Hubschle T, Kloeckener T, et al
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