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396 The PI3K/AKT/mTOR cascade is frequently dysregulated in ESCC

opt for small, frequent low-fat meals over large traditional ones

Titration takes 12-16 weeks: 2 mg, then 4 mg, then 8 mg, then up to 12 mg each step held for four weeks before escalating

1 At baseline, investigators noted the treatment and control groups did not differ significantly in terms of BMI, RA disease activity, disease-modifying antirheumatic drug use, or prednisone use