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Well be comparing both medications, including their efficacy, timelines, and practical considerations

Optimizing thyroid hormone replacement is the essential first stepensuring TSH levels are within the laboratory-specific reference range maximizes metabolic function and creates a more favorable environment for weight management

Cardiovascular outcome studies Although multiple clinical trials evaluating cardiovascular events associated with GLP-1 RA use as the primary outcome are currently ongoing (Table 1), abundant non-primary outcome data are available from many clinical trials on the efficacy of GLP-1 RAs marketed earlier, such as exenatide (DURATION studies) and liraglutide (LEAD studies)

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