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integrated EHR and genome-wide association studies (GWAS) data from the UK Biobank to recapitulate 46% of observed multimorbidities 16 , while Murrin et al
While four major defense systems, including the GPX4-GSH axis, FSP1-CoQ 10 pathway, DHODH-CoQ 10 system, and GCH1-BH4 pathway, are known to regulate redox homeostasis and lipid peroxidation, their inhibition elicits heterogeneous responses across PDAC models
Other choline metabolites known to be cell-signaling molecules include platelet-activating factor (PAF) and sphingophosphocholine
doi: 10.3389/fphys.2020.00694 256 SharmaA.TiwariS.DebM
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