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Research shows that people who used semaglutide had lower vitamin B12 levels (they also had bariatric surgery before using semaglutide), and another study concluded that people with obesity had lower B12 levels
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The fact that known stimuli for SS inhibition acting through adrenergic neurons (e.g., galanin and insulin hypoglycemia) are able to overcome the inhibitory effect of atropine on GH secretion is consistent with this theoretical scheme, which, moreover, does not exclude the possibility that the cholinergic input directly reaches SS neurons and inhibits them, as acetylcholine does in hypothalamic cultures
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