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[16] [121] Upon leaving the stomach the hydrochloric acid of the chyme is neutralized in the duodenum by bicarbonate, [122] and pancreatic proteases release the vitamin from HC, making it available to be bound by IF, which is a protein secreted by gastric parietal cells in response to the presence of food in the stomach

Structurally, the active cation (C 10 H 11 N 2 + , MW 159.21) is a methylated quinolinium ring carrying a 5-amino substituent

Vitamin B12: Health professional fact sheet

There can be secondary benefits to overall health and wellness markers when deficiency is corrected: better training quality, more stable mood, fewer days lost to drag