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Compounded versions of both medications are prescribed by weight loss physicians and dosed via weekly subcutaneous injection using a standard U-100 insulin syringe
, - (ob/ob) leptin, -GIPR "" , , (Zhang ' -Nature 1994, Vilsbll ' -Diabetologia 2002 -Yamada ' -Diabetes 2006)
Shi Q, Nong K, Vandvik PO et al (2023) Benefits and harms of drug treatment for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials
The SURMOUNT-1 Phase 3 trial published in the New England Journal of Medicine demonstrated 20.9% mean body weight reduction at 72 weeks on tirzepatide 15mg weekly versus 3.1% with placebo
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