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This is a direct contributor to wound closure strength and to the improved tensile properties observed in GHK-Cu-treated tissue
FIGURE 9 5.3.5 ROS promotes UPS-mediated acceleration of protein degradation The ubiquitin-proteasome system (UPS) is the primary protein degradation machinery in eukaryotic cells, responsible for removing misfolded, damaged, or excess proteins to maintain proteostasis and regulate key cellular processes including cell cycle and immune signaling (Peris-Moreno et al., 2021)
Zhang H, Liu H, Zhou L, Yuen J, Forman HJ
After 4 weeks the dose should be increased to 0.5mg once weekly
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