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A slight, ongoing B12 deficiency can damage the nervous system and cause the following symptoms: Fatigue or unexplained weakness Chest pain Loss of appetite Shortness of breath Depression Poor memory Although B12 deficiency isn't a widespread problem in general, it is typically seen in patients who are on extreme diets or have a disease that inhibits the body's ability to absorb B12 from food and beverages
Sources: National Institute of Health Vitamin B12 deficiency .
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An ice pack applied prior to injection also helps to dull the sensation and ease discomfort
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