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All cited studies are conducted in rodent or in-vitro systems consistent with RUO classification
Supporting chronic weight management in eligible adults with overweight or obesity when used with a reduced-calorie diet and increased physical activity
The highest results remain in the non-diabetic, non-cardiovascular-disease obesity trials (TRIUMPH-1 and TRIUMPH-4)
This receptor is also expressed, and hence can be studied, in vitro , by the human enteroendocrine cell model NCI-H716 or by the murine GLUTag cell line (320)
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