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In a randomized, placebo-controlled trial in 1,374 participants who had colonoscopic removal of at least one colorectal adenoma (the Selenium and Celecoxib trial), selenium supplementation (200 g/day with selenized yeast) for a median of 33 months had no effect on colorectal adenoma recurrence (88)
The effect of retatrutide on bone density is also yet to be seen, although other GLP-1s have been shown to cause a decrease in bone density proportional to weight loss
doi: 10.1038/nrrheum.2010.213 92 Martel-PelletierJLajeunesseDReboulPPelletierJP
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