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Their oxidation numbers are analogous since O and S are both in Group 6 of the periodic table and are more electronegative than C
The following GLP-1RAs showed a significantly higher odds ratio of discontinuation due to adverse events compared with placebo: lixisenatide (odds ratio 2.86 (95% confidence interval 1.48 to 5.51)), semaglutide (2.61 (1.56 to 4.37)), exenatide (2.39 (1.14 to 4.98)), tirzepatide (2.30 (1.30 to 4.09)), and liraglutide (2.15 (1.26 to 3.69)) (fig 8A)
The FDA approved Liraglutide, the first generic of a once-daily GLP-1 injection, in December 2024
Diabetes Care 2013;36:3620e6
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