glp-1 nature medicine This is a review of the drug class and what's coming down the pike; it's not about perioperative issues. Article PDF: https://bit.ly/New-GLP1s Unlocking the broad health benefits

Acceleration of Bone and Joint Recovery : Studies suggest that BPC-157 facilitates bone regeneration and joint repair by modulating osteoblast and chondrocyte activity

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Alcohol , especially excessive drinking and alcoholism, depletes folate [ R ] Niacin , high doses deplete methylation resources [ R ] Low stomach acid due to medications or other reasons can reduce folate absorption in the gut [ R ] Excessive SAM-e levels reduce MTHFR function [ R ] Smoking depletes folate [ R ] Chronic diseases/oxidative stress activate the enzyme GSK3B , which can inhibit MTHFR, especially in the presence of high SAM-e [ R ]

doi: 10.3389/fphar.2021.698153 83 MillerR