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Figure 2 4.1 Imaging of Gln metabolism predicts treatment response Abnormal Gln metabolism has facilitated the use of non-invasive imaging techniques for early tumor diagnosis and treatment monitoring, such as 18F-(2S,4R)-4-fluoroglutamine (18F-FGln) PET and L-( 18F-FGln and 11C-Gln are imaging agents used for assessing Gln metabolism in tumors

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Additionally, ferroptosis also plays a significant role in the onset and progression of female ovarian dysfunction, and it may induce ovarian dysfunction, damage pre-implantation embryos, reduce endometrial receptivity, and increase the crosstalk between diseases associated with subfertility [62, 63]

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