Prolonged or high-dose use of BPC-157 may carry a theoretical risk of vascular proliferation in undesired tissues, particularly in individuals with cancer or pre-existing vascular disease. Perovic, D
A 2011 mechanism paper by Chang and colleagues in Journal of Applied Physiology demonstrated that BPC-157 promotes tendon fibroblast outgrowth, supports fibroblast survival under oxidative stress, and facilitates cell migration through the FAK-paxillin signaling pathway a pathway central to cell adhesion and movement
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It can also affect the nervous system, leading to numbness, tingling, and memory problems