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Some people use GLP-1 medications for a defined period as part of an active weight loss phase, while others remain on them longer-term for weight management, particularly if weight regain is a clinical concern
More than 10 years ago, a compounding pharmacy in Massachusetts produced contaminated steroid spinal injections, in bulk, that resulted in a widespread fungal meningitis outbreak, injuring more than 700 patients and killing 100
Maintenance uses 1-2mg weekly thereafter
Studies in mice using several tissue-specific targeting strategies have confirmed that the elevation of circulating DPP4 in obesity is liver derived (2224), suggesting that DPP4 produced in the liver may primarily contribute to the progression of NAFLD (25)
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