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Vitamin B12 has a long history of effective subcutaneous delivery, with little to no muscle pain after B12 injections

This means the B12 component in a compounded semaglutide formulation is most likely to help patients who are deficient or at risk of deficiency, those eating very little, those following plant-based diets, older adults whose B12 absorption decreases with age, or those with conditions affecting B12 absorption like gastric bypass or certain GI conditions

However, studies suggest that supplementing with B12 does not reduce the risk of developing dementia or Alzheimers disease in older adults, or slow its progression

Better endurance, more reliable energy throughout the day, and a metabolism thats actually responding not fighting you at every turn