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NAC provides cysteine, one of the three amino acids that makes up GSH
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Hemodynamic advantages include enhanced control of afferent and efferent arterioles, mitigating hyperfiltration typical of early diabetic kidney disease
Absolute contraindications include personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), previous serious hypersensitivity to semaglutide or formulation components, pregnancy (the medication should be discontinued at least 2 months before planned conception), and breastfeeding due to insufficient data on excretion in human milk
