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Am J Clin Nutr 88:12421247 Lithell H, Bruce A, Gustafsson IB et al (1983) A fasting and vegetarian diet treatment trial on chronic inflammatory disorders
As an example, in the DURATION-8 study, while combination therapy produced greater HbA1c and body weight reductions, the effect was less than additive compared to the sum of individual drug effects, most likely because the efficacy of glucose-lowering therapies can depend on baseline glycaemic control [24]
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