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a published NMR analysis found an undeclared constituent in a custom-synthesised peptide (Choules et al., Journal of Pharmaceutical and Biomedical Analysis , 2020)
10.2337/dbi18-0008 77
Abbreviations ADVANCE: action in diabetes and vascular disease AMI: acute myocardial infarction BID: twice daily bpm: beats per minute CI: confidence interval CVOT: cardiovascular outcome trial ELIXA: Evaluation of LIXisenatide in Acute coronary syndrome FIGHT: Functional Impact of GLP-1 for Heart Failure Treatment GLP-1 RA: glucagon-like peptide-1 receptor agonist HF: heart failure HR: heart rate LAR: long-acting release LEADER: Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results LIVE: Effect of LIraglutide on left VEntricular function in chronic heart failure patients with and without type 2 diabetes LS: least squares PK: pharmacokinetic QD: once daily QW: once weekly SE: standard error T2DM: type 2 diabetes mellitus References Inzucchi SE, Bergenstal RM, Buse JB, Diamant M, Ferrannini E, Nauck M, Peters AL, Tsapas A, Wender R, Matthews DR
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