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Fen-phen, a combination of fenfluramine and phentermine, led to rapid weight loss and received comprehensive media coverage as a "miracle" drug
They stimulate the central nervous system (CNS) and are FDA-approved to treat attention-deficit hyperactivity disorder (ADHD), a neurodevelopmental disorder associated with hyperactivity, inattention, and impulsivity
It has also been reported to ameliorate the effects of reactive oxygen species (ROS) and free radical-induced oxidative stress (OS) and minimizing pathological disorders of sperm, like adenosine triphosphate (ATP) depletion leading to insufficient axonemal phosphorylation, lipid peroxidation as well as loss of motility and viability [9, 10]
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