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This review integrates current evidence on how brain peptides contribute to AD pathophysiology, summarizes recent progress in peptide-based therapeutic strategies and delivery platforms, and critically examines the remaining barriers to clinical translation, including bloodbrain barrier penetration, metabolic stability, off-target effects, and the need for biomarker-guided patient stratification
doi: 10.1038/s41416-019-0637-9 45 JiangBZhangJZhaoGLiuMHuJLinFet al
2025 Jul 12;44(7):116014
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