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These effects result from the peptide's ability to activate multiple growth factor pathways simultaneously, including TGF-, basic fibroblast growth factor (bFGF), and insulin-like growth factor-1 (IGF-1)

Elevated levels may signal impaired glucose tolerance or diabetes, which influences starting dosages and monitoring requirements

Activation of rodent adipocyte beta-3 receptors can promote cAMP signaling, stimulated lipolysis, and thermogenic responses