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Before attributing symptoms to histamine intolerance, other conditions should be excluded according to UK guidelines, including: Food allergies (following BSACI guidance) Irritable bowel syndrome (NICE CG61) Coeliac disease (NICE NG20) Inflammatory bowel disease Red flags that warrant further investigation include unintentional weight loss, gastrointestinal bleeding, persistent vomiting, and iron-deficiency anaemia

44 mmol/kg dry muscle)

Canagliflozin did not statistically significantly increase the risk for lower-limb amputations, fractures, acute kidney in- jury, or hyperkalemia but did increase the risk for diabetic ketoacidosis (2.2 and 0.2 events per 1000 patient-years in the canagliflozin and placebo groups, respectively)

"So often in eating disorder recovery we're obsessed with staying in the disorder, and then we become obsessed with the process of recovery, and that almost replaces the eating disorder," they explained