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This cell line has also been validated in a dose-response assay using a small molecule agonist, Danuglipron

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Additionally, IL-1beta is thought to be involved in amyloid precursor synthesis and the production of other cytokines involved with neurodegenerative disorders [58]

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The oxidation states of DJ-1 dictate the cell fate in response to oxidative stress triggered by 4-hpr: autophagy or apoptosis

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