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Cancer 19 , 625637 (2019)
A deficiency is characterised by megaloblastic anaemia, fatigue, weakness, constipation, loss of appetite, and weight loss
This selectivity is particularly important for individuals seeking pure fat reduction rather than body recomposition, those who do not want muscle hypertrophy for aesthetic or functional reasons, athletes in weight-class sports who need fat loss without muscle gain, individuals with contraindications to growth-promoting interventions, and those concerned about cell proliferation effects
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