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Immunohistochemical staining and quantification of positive cells confirmed decreased numbers of Doublecortin-like kinase protein 1 (Dclk1) + tuft cells but stable numbers of serotonin containing (5-HT + ) enterochromaffin cell under inflammatory conditions in IL-10 -/- mice ( Figure 2C,D ), suggesting mechanisms specifically sustaining this cell population under inflammatory conditions

Liraglutide (Victoza, Saxenda), administered once daily, has an intermediate half-life of approximately 13 hours and typically clears from the body within 3 days (about 5 half-lives) of discontinuation

This synergistic effect can be particularly beneficial for individuals suffering from conditions like arthritis or joint stiffness