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Trial averages at the highest dose (12 mg) reached around 24% body weight loss at 48 weeks, and around 28% at 68 weeks in the obesity plus knee osteoarthritis trial
Steroid Biochem.1986, 25 (5), 867-876 72
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The most commonly reported events in active arms were mild and transient: injection site reactions in some subcutaneous subjects, occasional headache, and in some oral dosing arms, minor gastrointestinal tolerance issues
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