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(2021) reported cytotoxic effects of Sitagliptin on TC cell lines TPC-1 and GLAG-66 as well as a reduction of cell proliferation in both TC cell lines
On the basis of cardiovascular outcomes trials (CVOTs) demonstrating reduced risks of major cardiovascular events (MACE), both GPL-1RAs and SGLT-2is are recommended for T2D patients with high cardiovascular risk [13]
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