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If you worry that your glutathione levels are not sufficient to counter the oxidative stress, toxins, inflammation, and other potential problems you may have, or if you have a chronic disease and are looking for natural ways to support the body and counter some of the symptoms and other effects of the disease, then talk with your doctor, nutritionist, or another healthcare provider

The suggestion is that reduced GR activity and therefore less 'reduced glutathione' may be implicated in Irritable Bowel Syndrome - possibly because it has less defenses against free radicals, the cause of oxidative stress

Mol Microbiol

204 Two meta-analyses also found acupuncture to be more effective than pharmaceutical treatment of IBS, and to have the least severe side effects