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Similarly, the substudy of the obesity phase 2 trial showed clear promise for retatrutide in the treatment of MASLD [47], and through its GCG receptor agonism, retatrutide may offer benefits beyond WL, through weight-independent metabolic effects at the liver [40]
With the average out-of-pocket cost for GLP-1s exceeding $1,000 per month without insurance, these medications remain unaffordable for many
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