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IGF-1 elevation : Chronic IGF-1 increase raises theoretical cancer risks and causes acromegalic changes

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One study in 50 patients with advanced gastric cancer receiving weekly cisplatin-based treatment reported that intravenous administration of 1.5 g/m 2 glutathione before treatment and then 600 mg intramuscularly on days two to five prevented neuropathy without affecting response to treatment (Cascinu 1995)