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Although US in a non-invasive and practical method, it has low sensitivity for mild levels of steatosis and cannot be used for the distinction between NAFLD and NASH, without a concomitant liver biopsy
The engineered strain W303-1b/FGP with three biosynthetic pathways presented the highest GSH concentration (216.50 mg/L) and GSH production of W303-1b/FGP was further improved by 61.37 % when amino acid precursors (5 mM glutamic acid, 5 mM cysteine and 5 mM glycine) were fed in shake flask cultures
Reznick AZ, Packer L (1994) Oxidative damage to proteins: spectrophotometric method for carbonyl assay
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