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For activity screening, we adapted a GSTO1 substrate assay that relies on the quantification of the reduction of S -(4-nitrophenacyl)glutathione (4-NPG), a GSTO1-specific substrate 17 , using recombinant human GSTO1 in a high-throughput screening format
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Now, it was a slow start though, Mike, because the history of drug development in obesity has been fraught with challenges
H., Arras, T., Becker, S., Holighaus, G., Ohlberger, G., & Unden, G
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