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The advantages of GLP-1 agonists include substantial clinical trial data supporting their efficacy and safety, FDA approval for weight management in certain populations, proven results with many users losing 15-20% or more of body weight, and effects on appetite that make caloric restriction feel natural
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I admit early on I didnt appreciate how serious these Herxheimer reactions could be
The integrated immunopathogenic framework linking gluten exposure, intestinal events, systemic immune activation, and thyroid autoimmunity is summarized in Figure 1
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