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Many perceived hunger signals are actually thirst signals
5 These guidelines align with the American Diabetes Association (ADA) standards of care which also provide strong recommendations based on robust clinical trial data supporting the cardiovascular benefits of GLP-1 RAs, particularly in patients with established cardiovascular disease and chronic kidney disease (CKD)
GLP-1 signaling reduces appetite and modulates reward, while GIP signaling enhances metabolic regulation and may have central nervous system effects
Inferring a specific gastric-emptying rate from a side-effect profile is a reasonable hypothesis, not a quantified result
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