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BDNF/NGF Pathway Enhancers (Lions Mane, 7,8-DHF) Mechanism: These aim to upregulate neurotrophins or mimic TrkB signaling, nudging plasticity
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From day 7 to day 10 the differences between control and AITC-treated seedlings were smaller than those observed during the second period, indicating that the effect of AITC on root growth persisted until day 10 but decreased over time (Supplementary Figure S2)
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 6-hydroxydopamine (6-OHDA), and 5-S-cysteinyl-dopamine (CysDA) models each target dopaminergic neurons and increase oxidative damage to the brain, providing valuable insight to the efficacy of mitigating oxidative stress as a mechanism of sulforaphanes neuroprotective effects
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