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El acceso y la disponibilidad pueden variar segn la regin, lo que puede influir en la decisin de tratamiento y requerir alternativas segn el contexto local
According to another study, glutaminolysis increases the level of -KG production, resulting in GTP loading of RagB and lysosomal translocation of the mTORC1 complex in human cancer cell lines 160
"With the socioeconomic constraints, the cost variables that are at play, we have huge concerns that a large percentage of our patient base that is reliant on compounded formularies that you can get for $100 to $200 a month and now they are faced with having to pay $1,000, we're concerned about where those patients are going to go," he said
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