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3 Here we describe an integrated chemical, pharmacological and structural approach to elucidate mechanisms of signal transduction by the glucagon-like peptide-1 receptor (GLP-1R), based on comparisons involving two natural agonists, GLP-1 and exendin-4, and rationally designed analogues of these peptides
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This is another important benefit of GLP-1s, as kidney disease is a common complication of diabetes
It is vital to take into account that AOXs should be given in proper dose and duration as excessive intake can lead to reductive stress (171, 172)
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