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Other notable adverse effects include: Injection site reactions (redness, itching, or discomfort) Fatigue Hypoglycemia (particularly when combined with insulin or sulfonylureas) Increased heart rate (mild elevation) Alopecia/hair loss (more common in weight management indication) Serious but less common risks include pancreatitis and gallbladder disease, which require prompt medical attention if symptoms develop

a STEP dose-ranging study showed that participants on 2.4 mg lost nearly twice as much weight as those on 1.0 mg, independent of baseline body weight (Wilding et al., 2021)

2021Y9138) and funding was acquired by Wei Wu

355 Overall, integrating proteomics, mass spectrometry, and bioinformatics facilitates the construction of more effective diagnostic and detection models based on lactylation, thereby contributing to disease prevention and treatment strategies