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Liraglutide, the molecule in Victoza, was approved by the FDA for type 2 diabetes in 2010

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discontinue if irritation persists

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Heart rate effects peak around week 24 of treatment and then decline at weeks 36 and 48 even with continued dosing

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Metformin carries a boxed warning for lactic acidosis and should not be taken by people with severe renal impairment or acute or chronic metabolic acidosis

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