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The study of bioprocesses dependent on vitamin B 12 forms has been ongoing for many decades due to their biomedical importance [2]
Consistent with previous studies, cotadutide outperformed GLP-1 alone (40 nmol/kg/day liraglutide) in achieving maximal weight loss in obese mice, and this was attributed to the increased energy expenditure (77)
However, scientific evidence is mixed, and more comprehensive research is needed
doi:10.1016/j.bbr.2019.112359 84
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