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For each eligible study, two authors (MM and AN) independently extracted data, which was then reviewed by a third author (JV) using a piloted spreadsheet, in accordance with Cochrane Collaboration guidelines ( Where relevant data were missing, attempts were made to contact corresponding authors

Also, be aware that red yeast rice may aggravate symptoms of a neurological disorder, as described in a recent case report noted in the Concerns and Cautions section of the Red Yeast Rice Review

Some patients with severe B12 deficiencies need daily B12 injections at least at the beginning of their treatment

Then, seven shots are given on alternate days