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Seriousbut rareside effects: gallbladder pain, pancreatitis, vision changes
Notably, while Wegovy was first approved in June 2021, high out-of-pocket costs, sparse insurance coverage, and factory-related shortages likely limited how many eligible people could obtain these medications early on, which might help explain the delay in declining surgery rates
95% CI: 0.36-0.84
Factors that would result in increased population adoption and utilization are: Growth in off-label use of GLP-1s marketed for diabetes as only Wegovy, Saxenda, and Zepbound (new to market) are approved for weight loss
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