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Temperature fluctuations inside a home refrigerator are normal, but the medication can tolerate brief exposure during transport or accidental removal
Stopping them, especially without lifestyle changes, can cause weight regain (1)
That said, the study states that those who experienced these reported them as being generally manageable, and that they improved over time
(PubMed) Mirvish SS, Wallcave L, Eagen M, Shubik P
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