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Its human clinical trial history two separate trials with no reported toxicity further differentiates it from peptides studied only in animal models

DNA Repair and Genomic Stability Pathways DNA repair pathways receive substantial enhancement, with 47 DNA repair genes stimulated

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It causes an immediate release of almost all the granules (containing serotonin, histamine, chemokines, cytokines, enzymes, heparin, and prostaglandins), which trigger itching, swelling, mucous, and anaphylaxis.[ref] A delayed response by mast cells comes from the formation of other mediators, such as prostaglandin D2