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The generation of oxidative DNA lesions, such as 8-oxoguanine (8-oxoG), is linked to the development of various cancers, including melanoma, while the accumulation of these lesions can compromise genomic stability, leading to mutations and the eventual transformation of normal cells into malignant ones 53

Specific inulin-type fructan fibers protect against autoimmune diabetes by modulating gut immunity, barrier function, and microbiota homeostasis

95% CI, 1.722.62 for GLP-1RA versus SGLT2i plus GLP-1RA) [63]

256 This apparent contradiction may reflect differences in the extent and context of acinar cell apoptosis